Research Article: 3-(Adamantan-1-yl)-4-ethyl-1H-1,2,4-triazole-5(4H)-thione

Date Published: May 01, 2012

Publisher: International Union of Crystallography

Author(s): Ali A. El-Emam, Nasser R. El-Brollosy, Hazem A. Ghabbour, Ching Kheng Quah, Hoong-Kun Fun.


In the title compound, C14H21N3S, the 1,2,4-triazole ring is nearly planar, with a maximum deviation of 0.003 (4) Å. In the crystal, mol­ecules are linked into inversion dimers by pairs of N—H⋯S hydrogen bonds.

Partial Text

For the biological activity of adamantane derivatives, see: Al-Omar et al. (2010 ▶); Al-Deeb et al. (2006 ▶); El-Emam et al. (2004 ▶); Kadi et al. (2007 ▶, 2010 ▶); Vernier et al. (1969 ▶). For the synthesis of the title compound, see: El-Emam & Ibrahim (1991 ▶). For related structures of adamantane derivatives, see: Almutairi et al. (2012 ▶); Al-Tamimi et al. (2010 ▶); Rouchal et al. (2010 ▶); Wang et al. (2011 ▶); Al-Abdullah et al. (2012 ▶). For standard bond-length data, see: Allen et al. (1987 ▶).