Research Article: 3D printing in medicine of congenital heart diseases

Date Published: December 1, 2016

Publisher: Springer International Publishing

Author(s): Shi-Joon Yoo, Omar Thabit, Eul Kyung Kim, Haruki Ide, Deane Yim, Anreea Dragulescu, Mike Seed, Lars Grosse-Wortmann, Glen van Arsdell.

http://doi.org/10.1186/s41205-016-0004-x

Abstract

Congenital heart diseases causing significant hemodynamic and functional consequences require surgical repair. Understanding of the precise surgical anatomy is often challenging and can be inadequate or wrong. Modern high resolution imaging techniques and 3D printing technology allow 3D printing of the replicas of the patient’s heart for precise understanding of the complex anatomy, hands-on simulation of surgical and interventional procedures, and morphology teaching of the medical professionals and patients. CT or MR images obtained with ECG-gating and breath-holding or respiration navigation are best suited for 3D printing. 3D echocardiograms are not ideal but can be used for printing limited areas of interest such as cardiac valves and ventricular septum. Although the print materials still require optimization for representation of cardiovascular tissues and valves, the surgeons find the models suitable for practicing closure of the septal defects, application of the baffles within the ventricles, reconstructing the aortic arch, and arterial switch procedure. Hands-on surgical training (HOST) on models may soon become a mandatory component of congenital heart disease surgery program. 3D printing will expand its utilization with further improvement of the use of echocardiographic data and image fusion algorithm across multiple imaging modalities and development of new printing materials. Bioprinting of implants such as stents, patches and artificial valves and tissue engineering of a part of or whole heart using the patient’s own cells will open the door to a new era of personalized medicine.

Partial Text

Congenital heart diseases are the most common significant birth defects with a live birth prevalence of 7.5 per 1000 [1]. Most congenital heart diseases causing significant hemodynamic and functional consequences require surgical repair. Modern imaging technologies including ultrasound, computed tomography (CT) and magnetic resonance (MR) provide accurate information regarding the anatomy and hemodynamic consequences of congenital heart disease. However, understanding of the surgical anatomy from the provided images requires a complicated process of mental reconstruction and can be often inadequate or wrong. In addition, communication among cardiologists, radiologists and surgeons is often difficult because of complex, diverse and controversial terms used in the description of congenital heart diseases, which may lead to misunderstanding of the surgical anatomy [2].

3D printing has found its niche applications in the medicine of congenital heart diseases. 3D print models allow instantaneous understanding of any complex anatomy and simulation or hands-on training of surgical and interventional procedures. It has made a small revolution in teaching and surgical practice. We expect that Hands-on surgical training (HOST) will soon become a mandatory component of the congenital heart disease surgery programs. 3D printing will expand its utilization with further improvement of imaging and printing technologies and development of new printing materials. Bioprinting and tissue engineering will open the door to the new era of personalized medicine.

 

Source:

http://doi.org/10.1186/s41205-016-0004-x

 

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