Research Article: 4β-Hy­droxy-12,13-ep­oxy­trichothec-9-ene

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Bi-Zeng Mao, Chao Huang, Yu-Zhe Chen, Zhen-Er Lv, Shao-Yuan Chen.

http://doi.org/10.1107/S1600536812012408

Abstract

The asymmetric unit in the crystal of the title compound, C15H22O3, contains two independent mol­ecules with similar structures. Each mol­ecule contains two six-membered rings and one five-membered ring. The five-membered ring displays an envelope conformation with the C atom linking the epoxy group as the flap, while the two six-membered rings show half-chair conformations. The two independent mol­ecules are linked by an O—H⋯O hydrogen bond. These dimers are further linked by O—H⋯O hydrogen bonds, forming supra­molecular chains running along the a axis.

Partial Text

For the applications of trichodermin derivatives, see: Wei et al. (1974 ▶); Zhang et al. (2007 ▶). For ring conformations, see: Cremer & Pople (1975 ▶). For a related structure, see: Chen et al. (2008 ▶).

 

Source:

http://doi.org/10.1107/S1600536812012408