Research Article: 4-[3-(Biphenyl-4-yl)-1-phenyl-4,5-di­hydro-1H-pyrazol-5-yl]-3-(4-meth­oxy­phen­yl)-1-phenyl-1H-pyrazole dioxane monosolvate

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Hoong-Kun Fun, Suhana Arshad, Shridhar Malladi, Arun M. Isloor, Kammasandra Nanjunda Shivananda.

http://doi.org/10.1107/S1600536812009117

Abstract

In the title compound, C37H30N4O·C4H8O2, the dihedral angle between the pyrazole and dihydro­pyrazole rings is 74.09 (10)°. In the crystal, the components are linked into centrosymmetric tetra­mers (two main mol­ecules and two solvent mol­ecules) by C—H⋯O hydrogen bonds. C—H⋯π and π–π [shortest centroid-centroid separation = 3.6546 (9) Å] inter­actions are also observed.

Partial Text

For the biological and pharmacological activity of pyrazolines, see, for example: Sahu et al. (2008 ▶). For ring conformations, see: Cremer & Pople (1975 ▶). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986 ▶). For standard bond lengths, see: Allen et al. (1987 ▶).

 

Source:

http://doi.org/10.1107/S1600536812009117