Research Article: 4-(3,4-Dimethyl-5-phenyl-1,3-oxazolidin-2-yl)-2-methoxy­phenol

Date Published: June 01, 2010

Publisher: International Union of Crystallography

Author(s): Mohd Razip Asaruddin, Habibah A Wahab, Nornisah Mohamed, Jia Hao Goh, Hoong-Kun Fun.


In the title compound, C18H21NO3, the oxazolidine ring adopts an envelope conformation with the N atom at the flap position. The two benzene rings make dihedral angles of 74.27 (14) and 73.26 (15)° with the mean plane through the oxazolidine ring. In the crystal structure, O—H⋯O and C—H⋯O hydrogen bonds connect adjacent mol­ecules into chains along [010] incorporating R22(8) loops and further stabilization is provided by weak inter­molecular C—H⋯π inter­actions.

Partial Text

For general background to and applications of the title oxazolidine compound, see: Fitzgerald et al. (2005 ▶); Kamat et al. (2000 ▶); Kumar et al. (2004 ▶); Walton et al. (2003 ▶). For graph-set descriptions of hydrogen-bond ring motifs, see: Bernstein et al. (1995 ▶). For a related structure, see: Duffy et al. (2004 ▶). For bond-length data, see: Allen et al. (1987 ▶). For the stability of the temperature controller used for the data collection, see: Cosier & Glazer (1986 ▶).




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