Research Article: 4-[(5,5-Dimethyl-3-oxocyclo­hex-1-en­yl)amino]­benzene­sulfonamide

Date Published: August 01, 2012

Publisher: International Union of Crystallography

Author(s): Mansour S. Al-Said, Mostafa M. Ghorab, Hazem A. Ghabbour, Ching Kheng Quah, Hoong-Kun Fun.


In the title compound, C14H18N2O3S, the cyclo­hexene ring exhibits a distorted half-chair conformation and its mean plane makes a dihedral angle of 46.18 (8)° with the benzene ring. In the crystal, mol­ecules are linked via N—H⋯O, N—H⋯(O,O) and C—H⋯O hydrogen bonds, forming a three-dimensional network.

Partial Text

For general background to and the pharmacological activities of related compounds, see: Drews (2000 ▶); Supuran (2008 ▶); Supuran & Scozzafava (2000 ▶); Boyd (1988 ▶); Ghorab et al. (2007 ▶, 2009 ▶, 2011 ▶). For standard bond-length data, see: Allen et al. (1987 ▶). For ring conformations, see: Cremer & Pople (1975 ▶).




0 0 vote
Article Rating
Notify of
Inline Feedbacks
View all comments