Research Article: (4-Chloro-2-fluoro­phen­yl)[1-(2,6-difluoro­phen­yl)but-3-en­yl]amine

Date Published: May 01, 2009

Publisher: International Union of Crystallography

Author(s): Hoong-Kun Fun, Sankappa Rai, Prakash Shetty, Arun M. Isloor, Suchada Chantrapromma.


In the mol­ecule of the title homoallylic amine, C16H13ClF3N, the dihedral angle between the two benzene rings is 84.63 (4)°. Weak intra­molecular N—H⋯F hydrogen bonds generate S(6) and S(5) ring motifs. In the crystal structure, weak inter­molecuar N—H⋯F hydrogen bonds link mol­ecules into centrosymmetric dimers which are arranged in mol­ecular sheets parallel to the ac plane.

Partial Text

For standard bond lengths, see Allen et al. (1987 ▶). For hydrogen-bond motifs, see Bernstein et al. (1995 ▶). For background to the bioactivity and applications of homoallylic amines, see: Edwards et al. (1998 ▶); Robert (1998 ▶); Sabine & Horst (1991 ▶); Xie et al. (1989 ▶). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986 ▶).




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