Date Published: June 01, 2010
Publisher: International Union of Crystallography
Author(s): Asmaa Saber, Hafid Zouihri, El Mokhtar Essassi, Seik Weng Ng.
The seven-membered fused-ring in the title compound, C10H10N2O·H2O, adopts a boat conformation (with the two phenylene C atoms representing the stern and the methylene C atom the prow). In the crystal, two benzodiazepinone molecules are linked about a center of inversion by diazepine–carbonyl N—H⋯O hydrogen bonds. The dimers are further linked by water–diazepine O—H⋯N hydrogen bonds, forming a linear chain.
For background to the synthesis and biological activity of benzodiazepines, see: Ahabchane et al. (1999 ▶). For the microwave-assisted synthesis, see: Koizumi (2006 ▶). For a related structure, see: Saber et al. (2010 ▶).