Date Published: July 01, 2012
Publisher: International Union of Crystallography
Author(s): Chennan Ramalingan, Seik Weng Ng, Edward R. T. Tiekink.
In the title compound, C26H27ClN2O, the piperidine ring has a chair conformation and all of the ring substituents at Csp3 atoms occupy equatorial positions. The dihedral angle formed between the phenyl rings is 48.11 (9)°. The chlorobenzene ring occupies a position orthogonal to the methoxy(methylidene)amine residue [N—O—C—C torsion angle = −87.90 (15)°]. The conformation about the imine C=N bond [1.278 (2) Å] is E, and the chloro substituent is anti to the piperidine N atom. Helical supramolecular chains along  are sustained by C—H⋯π interactions in the crystal packing.
For the biological activity of molecules having a 2,6-diarylpiperidine core, see: Ramachandran et al. (2011 ▶); Ramalingan et al. (2004 ▶). For the structure of the bromo derivative, see: Ramalingan et al. (2012 ▶). For the synthesis, see: Ramalingan et al. (2006 ▶).