Research Article: 5α-Hy­droxy­eudesm-4(15),11(13)-dien-8β,12-olide

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Xue Gao, Gang Chen.


The title compound, C15H20O3, a sesquiterpene lactone, was isolated from the aerial parts of Carpesium minus Hemsl. (Compositae). The mol­ecule is composed of three rings, with the two cyclo­hexane rings in chair conformations and the cyclo­pentane ring adopting a twist conformation. The A/B ring junction is trans-fused. The absolute configuration shown has been arbitrarily assigned. In the crystal, mol­ecules are linked into [100] chains by O—H⋯O hydrogen bonds.

Partial Text

For the isolation and biological activity of the title compound, see: Lee et al. (2002 ▶); Yang et al. (2002 ▶); Li et al. (2011 ▶). For conformational analysis, see: Cremer & Pople (1975 ▶).