Research Article: 5-Benzoyl-2-(1H-indol-3-yl)-4-(4-methyl­phen­yl)-4,5-dihydro­furan-3-carbonitrile

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): J. Suresh, R. Vishnupriya, P. Gunasekaran, S. Perumal, P. L. Nilantha Lakshman.


The furan ring in the title compound, C27H20N2O2, adopts a twisted conformation about the sp3—sp3 bond. The mol­ecular structure is stabilized by an intra­molecular C—H⋯O inter­action which generates an S(6) ring motif. The crystal packing is stabilized by N—H⋯O and C—H⋯O inter­actions generating centrosymmetric R22(18) and C(6) chain motifs, respectively. A weak C—H⋯π inter­action is also observed.

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For the biological importance of furan derivatives, see: Auvin & Chabrier De Lassauniere (2005 ▶). For hydrogen-bonding graph-set notation, see: Bernstein et al. (1995 ▶). For additional conformation analysis, see: Cremer & Pople (1975 ▶).