Research Article: (5-Bromo-2-hy­droxy­phen­yl)(4-propyl­cyclo­hex­yl)methanone

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Kang Meng, Miao Cao, Zhuo-Ling An, Jie Zhang, Li-Hong Liu.


In the title compound, C16H21BrO2, the cyclo­hexane ring adopts a chair conformation. The hy­droxy and carbonyl groups are involved in an intra­molecular O—H⋯O hydrogen bond. In the crystal, weak C—H⋯O inter­actions link the mol­ecules into zigzag chains along [010].

Partial Text

For details of the biological activity of SGLT2 inhibitors, see: Meng et al. (2008 ▶); Gao et al. (2010 ▶); Shao et al. (2011 ▶). For related structures, see: Robinson et al. (2002 ▶); Wang et al. (2011 ▶).