Date Published: April 01, 2011
Publisher: International Union of Crystallography
Author(s): Hong Dae Choi, Pil Ja Seo, Byeng Wha Son, Uk Lee.
In the title compound, C21H21FO3S, the cyclohexyl ring adopts a chair conformation. The 4-fluorophenyl ring makes a dihedral angle of 77.71 (4)° with the mean plane of the benzofuran fragment. In the crystal, molecules are linked through intermolecular C—H⋯O hydrogen bonds and aromatic π–π interactions between the furan rings of neighbouring molecules [centroid–centroid distance = 3.578 (2) Å].
For the biological activity of benzofuran compounds, see: Aslam et al. (2006 ▶); Galal et al. (2009 ▶); Khan et al. (2005 ▶). For natural products with benzofuran rings, see: Akgul & Anil (2003 ▶); Soekamto et al. (2003 ▶). For our previous structural studies of related 3-(4-fluorophenylsulfonyl)-2-methyl-1-benzofuran derivatives, see: Choi et al. (2010a ▶,b ▶).