Research Article: 5-Methyl-3,3-bis­(4-methyl­piperazin-1-yl)-1-[2-(4-methyl­piperazin-1-yl)eth­yl]indolin-2-one

Date Published: June 01, 2012

Publisher: International Union of Crystallography

Author(s): Hui-Hui Lin, Xiao-Lin Zheng, Sheng-Li Cao.


In the title compound, C26H43N7O, each piperazine ring adopts a chair conformation. Two 1-methyl­piperazine rings bond to one Csp3 of the pyrrole ring via the piperazine N atoms, while the third one links to the N atom of the indolin-2-one unit through a flexible ethyl group with an almost syn conformation. In the crystal, mol­ecules are connected through methyl­ene–carbonyl C—H⋯O inter­actions into an infinite chain along the c axis. The almost parallel arrays are stacked, forming a three-dimensional framework.

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For the background to indoline-2,3-dione and its derivatives, see Chiyanzu et al. (2005 ▶); Solomon et al. (2009 ▶); Sriram et al. (2004 ▶). For a related structure, see: Lin et al. (2012 ▶).




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