Research Article: 6β-Methyl-3,20-dioxopregn-4-en-17-yl acetate

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Longran Chen, Xuefen Liu, Peng Yang.

http://doi.org/10.1107/S1600536812008665

Abstract

The title compound, C24H34O4, is a precursor of Megestrol acetate. Ring A has a half-chair conformation [Q = 0.446 (3) Å, θ = 54.6 (4)° and ϕ = 9.5 (4)°]. Ring D adopts a 13β-envelope conformation [Q = 0.463 (2) Å and ϕ = 188.2 (3)°].

Partial Text

For the characterization of related structures, see: Evans & Boeyens (1989 ▶). Soriano-Garcia et al. (2005 ▶). Yousuf et al. (2011 ▶). For the physiological properties of the title compound, see: Mishell (1996 ▶).

 

Source:

http://doi.org/10.1107/S1600536812008665