Research Article: 6-[(2E)-3,7-Dimethyl­octa-2,6-dien-1-yl]-5,7-dihy­droxy-8-(2-methyl­butano­yl)-4-phenyl-2H-chromen-2-one–6-[(2E)-3,7-dimethyl­octa-2,6-dien-1-yl]-5,7-dihy­droxy-8-(3-methyl­butano­yl)-4-phenyl-2H-chromen-2-one (1/1) from Mesua elegans1

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Gomathi Chan, Khalijah Awang, Nor Hadiani Ismail, Seik Weng Ng, Edward R. T. Tiekink.

http://doi.org/10.1107/S1600536812008628

Abstract

The title co-crystal, C30H34O5·C30H34O5, comprises a 1:1 mixture of two mostly superimposed mol­ecules with the same chemical formula that differ in the nature of the substituent (2-methyl­butanoyl or 3-methyl­butano­yl) bound at the exocyclic ketone. The lactone ring is close to planar (r.m.s. deviation = 0.058 Å) and the phenyl ring is twisted out of this plane [dihedral angle = 60.08 (9)°]. The geranyl substituent is almost normal to benzene ring to which it is connected [C—C—Car—Car (ar = aromatic) torsion angle = −87.8 (2)°]. Intra­molecular O—H⋯O and O—H⋯π inter­actions are formed. In the crystal, supra­molecular chains are formed along the a axis owing to C—H⋯O contacts, with the lactone carbonyl atom accepting two such bonds.

Partial Text

For the spectroscopic characterization of the title material, see: Verotta et al. (2004 ▶) and for its acetyl­cholinesterase (AChE) inhibitory properties, see: Awang et al. (2010 ▶).

 

Source:

http://doi.org/10.1107/S1600536812008628