Date Published: April 01, 2012
Publisher: International Union of Crystallography
Author(s): Gomathi Chan, Khalijah Awang, Nor Hadiani Ismail, Seik Weng Ng, Edward R. T. Tiekink.
The title co-crystal, C30H34O5·C30H34O5, comprises a 1:1 mixture of two mostly superimposed molecules with the same chemical formula that differ in the nature of the substituent (2-methylbutanoyl or 3-methylbutanoyl) bound at the exocyclic ketone. The lactone ring is close to planar (r.m.s. deviation = 0.058 Å) and the phenyl ring is twisted out of this plane [dihedral angle = 60.08 (9)°]. The geranyl substituent is almost normal to benzene ring to which it is connected [C—C—Car—Car (ar = aromatic) torsion angle = −87.8 (2)°]. Intramolecular O—H⋯O and O—H⋯π interactions are formed. In the crystal, supramolecular chains are formed along the a axis owing to C—H⋯O contacts, with the lactone carbonyl atom accepting two such bonds.
For the spectroscopic characterization of the title material, see: Verotta et al. (2004 ▶) and for its acetylcholinesterase (AChE) inhibitory properties, see: Awang et al. (2010 ▶).