Date Published: July 01, 2012
Publisher: International Union of Crystallography
Author(s): Yanfeng Wang, Xinhui Pan, Dexiu Liu, Hong-Xiang Lou.
The title compound, C11H9F3O5, crystallizes with three molecules in the asymmetric unit. One –CF3 group is disordered by rotation, with the F atoms split over two sets of sites with occupancies which converged to 0.888 (6) and 0.112 (6). Weak π–π interactions are observed between adjacent benzene rings [the shortest centroid–centroid distance is 3.8858 (4) Å], resulting in the formation of a supramolecular chain along .
For the enhancement of the biological activity of F and CF3 containing molecules compared to their unfluorinated analogues, see: Vrábel et al. (2007 ▶); Wilson & Danishefsky (2010 ▶); Bravo et al. (1994 ▶); Jung et al. (2002 ▶). For the synthesis of the title compound, an intermediate for the synthesis of biologically active compounds, see: Corey et al. (1996 ▶); Weeratunga et al. (1987 ▶); Wu et al. (2004 ▶).