Research Article: (6S,7S,8S,8aS)-6-Ethyl-3-oxo-1,2,3,5,6,7,8,8a-octa­hydro­indolizine-7,8-diyl diacetate

Date Published: March 01, 2012

Publisher: International Union of Crystallography

Author(s): Viktor Vrábel, Ľubomír Švorc, Peter Šafář, Štefan Marchalín.

http://doi.org/10.1107/S1600536812005144

Abstract

In the mol­ecular structure of the title compound, C14H21NO5, the six-membered ring of the indolizine moiety adopts a chair conformation. There are two independent mol­ecules in the asymmetric unit. The oxopyrrolidine ring attached to the indolizine ring system is nearly planar, with mean deviations of 0.018 (3) and 0.010 (3) Å for the two mol­ecules. The absolute configuration of the title compound was assigned from the synthesis.

Partial Text

For indolizine derivatives, see: Gubin et al. (1992 ▶); Gupta et al. (2003 ▶); Liu et al. (2007 ▶); Medda et al. (2003 ▶); Molyneux & James (1982 ▶); Nash et al. (1988 ▶); Pearson & Guo (2001 ▶); Ruprecht et al. (1989 ▶); Smith et al. (2007 ▶); Teklu et al. (2005 ▶). For ring conformations, see: Cremer & Pople (1975 ▶). For the synthesis, see: Šafář et al. (2010 ▶). For related structures, see: Brown & Corbridge (1954 ▶); Pedersen (1967 ▶).

 

Source:

http://doi.org/10.1107/S1600536812005144