Date Published: July 01, 2012
Publisher: International Union of Crystallography
Author(s): Shuo Wang, Guangzhi Shan, Huiyuan Guo, Mingliang Liu.
In the title structure, C25H24FN3O5, a strong intramolecular O—H⋯O hydrogen bond is present between the carboxy group at the 3-position and the carbonyl group at the 4-position. In the crystal, molecules are held together by weak C—H⋯O, C—H⋯F and π–π [centroid–centroid distance 3.6080 (8) Å] interactions. The 1,4-dihydroquinoline ring and cyclopropyl group are not in the same plane, making an interplanar angle of 57.52 (8)°.
For the synthesis and properties of quinolone derivatives, see Basuri et al. (2011 ▶); Feng et al. (2011 ▶); Guo et al. (2011 ▶); Liu et al. (2010 ▶); Sharma et al. (2010 ▶); Xu et al. (2007 ▶). For the cryogenic cooler used in the data collection, see Cosier & Glazer (1986 ▶). For hydrogen bonding, see Desiraju & Steiner (1999 ▶).