Date Published: March 01, 2012
Publisher: International Union of Crystallography
Author(s): Hong Chen, Quan-Bin Liao.
In the title compound, C26H27ClN4OS, the thienopyrimidine fused-ring system is close to coplanar (r.m.s. deviation = 0.0089 Å), with a maximum deviation of 0.0283 (17) Å for the N atom adjacent to the benzene ring. This ring system forms dihedral angles of 83.51 (3) and 88.20 (5)° with the adjacent benzyl and phenyl rings, respectively. In the crystal, N—H⋯Cl interactions and C—H⋯O hydrogen bonds are observed.
For the biological and pharmaceutical properties of compounds containing a fused thienopyrimidine system, see: Amr et al. (2010 ▶); Huang et al. (2009 ▶); Jennings et al. (2005 ▶); Kikuchi et al. (2006 ▶); Mavrova et al. (2010 ▶); Santagati et al. (2002 ▶). For similar crystal structures, see: Xie et al. (2008 ▶); Chen et al. (2011 ▶).