Research Article: 7-Chloro-5-(chloro­meth­yl)pyrazolo­[1,5-a]pyrimidine-3-carbonitrile

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Jingli Xu, Hang Liu, Guixia Li, Chuanmin Qi.


All non-H atoms of the title compound, C8H4Cl2N4, are essentially coplanar, with an r.m.s. deviation of 0.011 Å. In the crystal, weak C—H⋯N hydrogen bonds link the mol­ecules into infinite sheets parallel to the bc plane.

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For details of the synthesis, see: Li et al. (2006 ▶). For applications of pyrazolo­[1,5-a]pyrimidines as pharmacophores or building blocks in anti-tumor drug design, see: Li et al. (2006 ▶); Di Grandi et al. (2009 ▶); Powell et al. (2007 ▶); Gopalsamy et al. (2005 ▶).