Research Article: 7-Hy­droxy-1,2,3,4-tetra­hydro­quinolin-2-one dihydrate

Date Published: July 01, 2012

Publisher: International Union of Crystallography

Author(s): Qian-Shou Zong, Jian-Yi Wu.

http://doi.org/10.1107/S1600536812025263

Abstract

The asymmetric unit of the title compound, C9H9NO2·2H2O, comprises two independent organic mol­ecules and four water mol­ecules of crystallization. The heterocyclic rings are not planar: in one mol­ecule, the C atom bearing the O atom and the adjacent methyl­ene C atom are displaced by 0.320 (3) and 0.677 (3) Å, respectively, from the other eight atoms of the fused ring system. Equivalent values of 0.243 (3) and 0.659 (3) Å apply to the second mol­ecule. In the crystal, the components are linked by N—H⋯O and O—H⋯O hydrogen bonds, forming a three-dimensional network.

Partial Text

For background to quinolin-2-ones as drugs, see: Braun et al. (2009a ▶,b ▶).

Source:

http://doi.org/10.1107/S1600536812025263