Research Article: A cocrystal of 3α-hy­droxy­tirucalla-8,24-dien-21-oic acid and 3β-fluoro­tirucalla-7,24-dien-21-oic acid (0.897:0.103)

Date Published: April 01, 2011

Publisher: International Union of Crystallography

Author(s): S. Yousuf, R. S. T. Kamdem, P. Wafo, B. T. Ngadjui, Hoong-Kun Fun.


The title compound, 0.897C30H48O3.0.103C30H47O2F is a co-crystal of two triterpenes isolated from the resin of Canarium schweinfurthiiand Engl. Both triterpenes consists of four trans-fused rings having chair/half-chair/half-chair and envelope conformations. The mol­ecular conformations are stabilized by intra­molecular C—H⋯O hydrogen bonds, forming rings of S(7) graph-set motif. In the crystal, mol­ecules are linked by inter­molecular O—H⋯O and C—H⋯O inter­actions, forming sheets parallel to (001). All atoms. excepting the axially-oriented hydroxyl group in the major component and the equatorially-oriented fluorine atom in the minor component, are overlapping.

Partial Text

For the crystal structure of 3α-hy­droxy­tirucalla-7,24-diene-21-oic acid, see: Mora et al. (2001 ▶). For the crystal structure of 3α-hy­droxy­tirucalla-8,24-diene-21-oic acid, see: Yousuf et al. (2011 ▶). For the biological activity of canarium schweinfurthiiand, see: Atawodi (2010) ▶; Dongmo et al. (2010 ▶). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986 ▶).




0 0 vote
Article Rating
Notify of
Inline Feedbacks
View all comments