Date Published: June 20, 2004
Publisher: Public Library of Science
Partial Text: The announcement of the human genome sequence three years ago was widely hailed as one of the great scientific achievements in modern history, and with good reason. Determining the structure and nature of the genetic code promises to provide valuable insights into human evolution and the molecular basis of disease. But sequencing the genome is just the first step toward this decidedly worthy goal—the monumental task of ascribing biological meaning to those sequences has just begun. And while researchers know a great deal about some of the 30,000 or so genes in the human genome, they have yet to ascribe function to the majority of them. Takashi Gojobori and a large international team of collaborators have now taken a big step toward narrowing this knowledge gap.