Research Article: Antibody Responses to Mycoplasma pneumoniae: Role in Pathogenesis and Diagnosis of Encephalitis?

Date Published: June 12, 2014

Publisher: Public Library of Science

Author(s): Patrick M. Meyer Sauteur, Bart C. Jacobs, Emiel B. M. Spuesens, Enno Jacobs, David Nadal, Cornelis Vink, Annemarie M. C. van Rossum, Kasturi Haldar.


Partial Text

The pathogenesis of encephalitis associated with the respiratory pathogen Mycoplasma pneumoniae is not well understood. A direct infection of the central nervous system (CNS) and an immune-mediated process have been discussed [1]. Recent observations suggest that intrathecally detectable antibodies against the bacterium, which can serve to establish the etiology of encephalitis, may indeed mediate the disease.




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