Research Article: Antioxidant, antihypertensive, anti-hyperglycemic, and antimicrobial activity of aqueous extracts from twelve native plants of the Yucatan coast

Date Published: March 27, 2019

Publisher: Public Library of Science

Author(s): Cecilia Mónica Rodríguez-García, Jorge Carlos Ruiz-Ruiz, Leticia Peraza-Echeverría, Sergio Rubén Peraza-Sánchez, Luis Wiliunfo Torres-Tapia, Daisy Pérez-Brito, Raúl Tapia-Tussell, Francisco Gilberto Herrera-Chalé, Maira Rubí Segura-Campos, Andrés Quijano-Ramayo, Jesús Manuel Ramón-Sierra, Elizabeth Ortiz-Vázquez, Vijai Gupta.

http://doi.org/10.1371/journal.pone.0213493

Abstract

Looking for a biotechnical potential, aqueous extracts of leaves of 12 native species used in the Mayan traditional medicine of the coastal dune and mangrove of Yucatan (Mexico) were selected to evaluate their biological activities. Rhizophora mangle and Manilkara zapota showed the highest free radical scavenging activity (3.94 ± 0.19 and 6.42 ± 0.32 μg/mL, respectively), and the highest antihypertensive activity was obtained from Solanum donianum (0.38 μg/mL). The anti-hyperglycemic activity of these species was also tested; the highest activities were registered with R. mangle. The antimicrobial activity of Malvaviscus arboreus, S. donianum, M. zapota, and R. mangle at 10% (w/v) was positive against six human pathogenic bacteria and Bonellia macrocarpa against one pathogenic fungus. Solanum donianum, M. zapota, B. macrocarpa, and R. mangle were positive against two pathogenic plant fungi. These results show that the aqueous extracts of five native plants of the Yucatan coast have potential as antioxidants, ACE inhibitors, α-amylase and α-glucosidase inhibitors, and as antimicrobials, which make their exploration for utilization in the agricultural and pharmaceutical industries a possibility.

Partial Text

Natural products coming from plants have been an axis of the Mayan traditional medicine, and they remain regularly in use today. Recently, the ethnomedicinal knowledge of 100 species from 680 registered in the Yucatan peninsula was published [1]. Nevertheless, until today, the ethnomedicinal knowledge of the coastal dune and mangrove of Yucatan State, where plant species are growing with extreme climatological conditions, has not been reported. As a consequence, they produce metabolites that could have some biological activity (e.g. antioxidant, antimicrobial), which could be a biotechnological potential target in the health and agricultural sectors.

 

Source:

http://doi.org/10.1371/journal.pone.0213493

 

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