Research Article: Cinnarizinium picrate

Date Published: June 01, 2012

Publisher: International Union of Crystallography

Author(s): Yanxi Song, C. S. Chidan Kumar, G. B. Nethravathi, S. Naveen, Hongqi Li.


In the title salt {systematic name: 4-diphenyl­methyl-1-[(E)-3-phenyl­prop-2-en-1-yl]piperazin-1-ium 2,4,6-trinitro­pheno­late), C26H29N2+·C6H2N3O7−, the cinnarizinium cation is protonated at the piperazine N atom connected to the styrenylmethyl group; the piperazine ring adopts a distorted chair conformaiton. In the crystal, bifurcated N—H⋯(O,O) hydrogen bonds link the components into two-ion aggregates.

Partial Text

For background to the anti-histamine cinnarizine, see: Towse (1980 ▶); Barrett & Zolov (1960 ▶). For related structures, see: Mouillé et al. (1975 ▶); Bertolasi et al. (1980 ▶); Jasinski et al. (2011 ▶). For additional conformational analysis, see: Cremer & Pople (1975 ▶).




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