Date Published: March 27, 2007
Publisher: Public Library of Science
Author(s): Seth Kalichman, Lisa Eaton, Steven Pinkerton
Partial Text: Three randomized controlled trials (RCTs) of male circumcision (MC) have been halted when interim analyses showed significant reductions in HIV infection among men who received this intervention [1–3]. Modeling suggests that increased MC coverage in southern Africa could prevent as many as 2 million HIV infections over ten years . Moreover, the cost-effectiveness analysis by Kahn et al. recently published in PLoS Medicine indicates that MC could be cost-saving . However, the protection of MC may be partially offset by increased HIV risk behavior, or “risk compensation,” especially reduction in condom use or increases in numbers of sex partners. Risk compensation occurs when individuals adjust their behavior in response to perceived changes in their vulnerability to a disease . Risk compensation may be especially important for MC because avoiding the sexual dissatisfactions of condom use and the desire to have more sex partners are likely to be significant motivations for men to seek circumcision . In South Africa, 73% of men between the ages of 15 and 24 report using condoms during the last time they had sex . It is difficult to imagine a convincing public health message that effectively influences men to undergo circumcision and continue to consistently use condoms.