Date Published: July 18, 2012
Publisher: Hindawi Publishing Corporation
Author(s): J. C. Verster, O. Berthélemy.
A consumer satisfaction study was conducted to examine the effectiveness on hangover of After-Effect©, a new food supplement dedicated to improve well-being after an occasion of alcohol consumption. N = 113 persons were invited to participate in a home-based open label study to test the effectiveness of After-Effect©. On a night when they intended to consume alcohol, three pills were taken before alcohol consumption and two pills afterwards, before going to bed. The following day, participants completed a survey on the amount of alcohol consumed, hangover symptom severity, and satisfaction of the product. N = 103 participants completed the study. 88% of participants reported After-Effect© to be effective in reducing alcohol hangover. After-Effect© significantly improved overall hangover severity, and all individual hangover symptoms, except for palpitations. In addition, a significant reduction (P = 0.0001) in the severity score on concentration problems was reported when using After-Effect©. No gender differences were observed, and there was no relationship with the number of alcoholic drinks that were consumed. Consumers were satisfied with the product. In conclusion, consumer satisfaction and hangover severity scores suggest that After-Effect© may be effective in reducing alcohol hangover. However, controlled, double-blind clinical trials should confirm these findings.
Alcohol hangovers are the most commonly reported negative consequence of heavy drinking. About 80% of drinkers acknowledge having experienced a hangover at least once during the past year , a finding that is corroborated by clinical trials indicating that around 20% of drinkers are resistant to hangover . Alcohol hangovers are characterized by a feeling of general misery, and several symptoms such as headache, thirst, sleepiness, and concentration problems are commonly reported .
A total of 113 persons were contacted by telephone to participate in the study. Participants were selected randomly among consumers that were registered in the panel of the consumer testing laboratory TechniSens. If they agreed to participate after the telephone contact, they received After-Effect©, instructions for use and the survey by regular mail. Informed consent was obtained from all subjects. The study took place on 1–15 September, 2010. Subjects were instructed to use After-Effect© in an evening when they expected to consume a sufficient quantity of alcohol to leave them feeling unpleasant the following day. In that evening, participants were instructed to take 3 capsules of After-Effect© before drinking and 2 capsules at bedtime. They were instructed to swallow the capsules with a glass of water and not to chew them. A survey was completed the day after the drinking session, as soon as they presumed their blood alcohol level had returned to zero. The completed surveys were returned by email to TechniSens.
A total of 113 subjects participated in the study. Ten were excluded from the statistical analyses because they reported vomiting in the evening when they consumed alcohol and used After-Effect©. 103 subjects (21% men and 79% women) completed the study. Half of them were 25–30 years old, 25% were 31–35 years old, and 25% were 36–40 years old. In the evening out, 44% consumed 4–6 alcoholic consumptions, 46% consumed 7–9 alcoholic consumptions, and 10% more than 10 alcoholic drinks. Hangover symptom severity, with and without using After-Effect©, is summarized in Table 2.
The results from this open-label study suggest that After-Effect© is likely to reduce the presence and severity of alcohol hangover symptoms. Consumer satisfaction scores confirm these findings. The significant reduction in concentration problems after using After-Effect© is promising, because this may have a positive impact on cognitive and psychomotor impairment that is generally seen during alcohol hangover.