Research Article: Dichloridobis[ethyl 2-(2-amino-1,3-thia­zol-4-yl)acetate-κ2O,N3]cadmium

Date Published: June 01, 2012

Publisher: International Union of Crystallography

Author(s): Lai-Jun Zhang, Fa-Yun Chen, Guang-Yi Liu, Xiao Chen, Zhi-Feng Chen.


The asymmetric unit of the title compound, [CdCl2(C7H10N2O2S)2], contains two complex molecules with similar configurations. The CdII atoms are each six-coordinated by two thiazole N and two carbonyl O atoms from the 2-(2-amino-1,3-thiazol-4-yl)acetate ligand, and by two Cl− anions in a distorted octa­hedral geometry. In the crystal, intra- and inter­molecular N—H⋯Cl hydrogen bonds create parallel chains along [1-10]. C—H⋯Cl inter­actions also occur.

Partial Text

For the pharmacological activity, including anti­tumor activity, of metal complexes with thia­zole ligands, see: Alexandru et al. (2010 ▶); Chang et al. (1982 ▶). For related structures and preparative procedures, see: Alexandru et al. (2010 ▶); He et al. (2009 ▶); Siddiqui et al. (2009 ▶); Yang et al. (2009 ▶); Usman et al. (2003 ▶); Zhang et al. (2008a ▶,b ▶, 2009 ▶).