Research Article: Diethyl 2,6-dihy­droxy-4-(3-nitro­phen­yl)-2,6-bis­(trifluoro­meth­yl)piperidine-3,5-dicarboxyl­ate

Date Published: February 01, 2012

Publisher: International Union of Crystallography

Author(s): Hoong-Kun Fun, Suhana Arshad, B. Palakshi Reddy, V. Vijayakumar, S. Sarveswari.

http://doi.org/10.1107/S1600536811055346

Abstract

In the title compound, C19H20F6N2O8, the eth­oxy and ethyl groups are disordered over two sets of sites, with occupancy ratios of 0.212 (18):0.788 (18) and 0.746 (6):0.254 (6), respectively. The piperidine ring adopts a chair conformation. In the mol­ecule, intra­molecular O—H⋯O hydrogen bonds form two S(6) ring motifs. In the crystal, mol­ecules are linked via O—H⋯O and C—H⋯O hydrogen bonds, forming dimers.

Partial Text

For studies on 1,4-dihydro­pyridine and piperidones reported by our group, see: Palakshi Reddy et al. (2011a ▶,b ▶,c ▶); Rathore et al. (2009 ▶); Rajesh et al. (2011 ▶). For bond-length data, see: Allen et al. (1987 ▶). For hydrogen-bond motifs, see: Bernstein et al. (1995 ▶). For ring conformations, see: Cremer & Pople (1975 ▶).

 

Source:

http://doi.org/10.1107/S1600536811055346