Date Published: June 01, 2010
Publisher: International Union of Crystallography
Author(s): Tara Shahani, Hoong-Kun Fun, B. Palakshi Reddy, V. Vijayakumar, S. Sarveswari.
In the title compound, C19H23NO6, the 1,4-dihydropyridine ring is twisted slightly from planarity, with a maximum deviation of 0.101 (1) Å, and adopts a very flattened boat conformation. The dihedral angle formed between the plane through the four C atoms of the 1,4-dihydropyridine ring and the benzene ring is 84.67 (7)°. In the crystal structure, intermolecular N—H⋯O and C—H⋯O hydrogen bonds link the molecules into a three-dimensional network.
For background to the biological activity of 1,4-dihydropyridines, see: Gaudio et al. (1994 ▶); Bocker & Guengerich (1986 ▶); Gordeev et al. (1996 ▶); Sunkel et al. (1992 ▶); Vo et al. (1995 ▶); Cooper et al. (1992 ▶). For the synthesis of Hantzsch pyridines, see: Rathore et al. (2009 ▶). For a related structure, see: Shahani et al. (2009 ▶). For reference bond-length data, see: Allen et al. (1987 ▶). For puckering parameters, see: Cremer & Pople (1975 ▶). For the stability of the temperature controller used for the data collection, see: Cosier & Glazer (1986 ▶).