Date Published: May 01, 2012
Publisher: International Union of Crystallography
Author(s): Nan Jiang, Jian Zuo, Haiyan Wang, Ming Han, Xin Zhai.
In the title compound, C20H25ClN62+·2ClO4−, the organic cation is roughly planar, as shown by the dihedral angle of 3.78 (3)° between the quinazoline and chlorophenyl rings. The quinazoline ring is itself approximately planar, with an average deviation of 0.018 (4) Å. The organic cation adopts an E configuration with respect to the C= N double bond of the hyrazinyl group. The (dimethylazaniumyl)propylamino side chain is disordered over two sets of sites with occupancies of 0.768 (10) and 0.232 (10). In the crystal, two cations and four anions are linked by strong N—H⋯O hydrogen bonds. Weak C—H⋯O hydrogen bonds exist among these aggregates.
For antitumor background to the title compound, see: Abouzid & Shouman (2008 ▶); Zhang et al. (2008 ▶); An et al. (2010 ▶); Horiuchi et al. (2009) ▶. For the structures of closely related compounds, see: Fun et al. (2010 ▶); Ferreira et al. (2009 ▶); de Souza et al. (2010 ▶); Loh et al. (2011 ▶).