Research Article: (E)-3-(4-Chloro­phen­yl)-1-(5-hy­droxy-2,2-dimethyl-2H-chromen-6-yl)prop-2-en-1-one

Date Published: February 01, 2012

Publisher: International Union of Crystallography

Author(s): Jie Tang, Jin-ying Chen, Ling-qun Jiang.


There are two independent mol­ecules in the asymmetric unit of the title compound, C20H17ClO3, each having an E configuration about the –C=C– bond. The dihedral angles between the two benzene rings in the two mol­ecules are 7.17 (11) and 9.82 (11)°. In both mol­ecules, the hy­droxy group is involved in an intra­molecular O—H⋯O hydrogen bond.

Partial Text

For the biological activity of chalcones, see: Tran et al. (2009 ▶); Rao et al. (2004 ▶); Opletalova & Sedivy (1999 ▶); Dimmock et al. (1999 ▶). For related structures, see: Boeck et al. (2006 ▶); Jasinski et al. (2009 ▶); Wang & Yang (2011 ▶). For the synthesis of a related compound, see: Krohn et al. (2002 ▶).