Research Article: (E)-3-Propoxymethyl­idene-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one monohydrate

Date Published: May 01, 2010

Publisher: International Union of Crystallography

Author(s): Burkhon Zh Elmuradov, Kambarali Turgunov, Bakhodir Tashkhodjaev, Khusniddin M. Shakhidoyatov.

http://doi.org/10.1107/S1600536810014303

Abstract

The title compound, C15H16N2O2·H2O, was synthesized via the alkyl­ation of 3-hydroxy­methyl­idene-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one with n-propyl iodide in the presence of sodium hydroxide. The organic mol­ecule and the water mol­ecule both lie on a crystallographic mirror plane. In the crystal structure, inter­molecular O—H⋯O and O—H⋯N hydrogen bonds link the components into extended chains along [100].

Partial Text

For the synthesis of the title compound and its derivatives, see: Späth & Platzer, (1935 ▶); Shakhidoyatov et al. (1976 ▶); Oripov et al. (1979 ▶); Elmuradov et al. (2006 ▶); Elmuradov & Shakhidoyatov (2004 ▶); Jahng et al. (2008 ▶). For the physiological activity of the title compound and its derivatives, see: Amin & Mehta (1959 ▶); Chatterjee & Ganguly (1968 ▶); Yakhontov et al. (1977 ▶); Yunusov et al. (1978 ▶); Johne (1981 ▶); Shakhidoyatov (1988 ▶). For standard bond distances, see: Allen et al. (1987 ▶).

 

Source:

http://doi.org/10.1107/S1600536810014303

 

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