Research Article: (E)-N′-Hy­droxy-1,3-diphenyl-4,5-di­hydro-1H-pyrazole-5-carboximidamide

Date Published: June 01, 2012

Publisher: International Union of Crystallography

Author(s): Chandra, N. Srikantamurthy, K. B. Umesha, S. Jeyaseelan, M. Mahendra.


In the mol­ecule of the title compound, C16H16N4O, the pyrazole ring makes dihedral angles of 8.52 (13) and 9.26 (12)° with the phenyl rings. The dihedral angle between the benzene rings is 1.86 (13)°. In the crystal, mol­ecules are linked into centrosymmetric dimers via pairs of O—H⋯N hydrogen bonds. Weak N—H⋯N inter­actions connect the dimers into a chain along the [100] direction. The pyrazole ring adopts a highly flattened envelope conformation.

Partial Text

For the biological activity of pyrazoles, see: Da Sliva et al. (2010 ▶); Farag et al. (2010 ▶); Khode et al. (2009 ▶); Boschi et al. (2011 ▶); Ghorab et al. (2010 ▶); Husain et al. (2008 ▶); Taj et al. (2011 ▶); Mikhaylichenko et al. (2009 ▶). For bond-length data, see: Allen et al. (1987 ▶). For puckering parameters, see: Cremer & Pople (1975 ▶). For a related structure, see: Fun et al. (2011 ▶).




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