Research Article: Ethyl 3-acetyl-4-(3-meth­oxy­phen­yl)-6-methyl-2-sulfanyl­idene-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

Date Published: May 01, 2012

Publisher: International Union of Crystallography

Author(s): Nikhath Fathima, H Nagarajaiah, Noor Shahina Begum.

http://doi.org/10.1107/S1600536812017679

Abstract

In the title compound, C17H20N2O4S, the aryl ring is positioned perpendicular to the dihydro­pyrimidine ring, the dihedral angle between the ring planes being 77.48 (9)°. The carboxyl­ate and methyl groups are in a cis conformation with respect to the C=C bond. The dihydro­pyrimidine ring adopts a twist-boat conformation. The crystal structure is stabilized by N—H⋯O and C—H⋯O inter­actions, the former resulting in mol­ecular chains along the b axis and the latter forming inversion dimers.

Partial Text

For the biological activity of dihydro­pyrimidines, see: Kappe (2000 ▶). For a related structure, see: Begum & Vasundhara (2009 ▶).

 

Source:

http://doi.org/10.1107/S1600536812017679