Research Article: Ethyl 4-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinoline-4-carboxyl­ate

Date Published: March 01, 2012

Publisher: International Union of Crystallography

Author(s): Xing-Yao Li, Jin-Long Wu.


In the title compound, C13H13NO4, the fused-ring system is nearly planar, with an r.m.s. deviation of 0.0408 Å. In the crystal, mol­ecules are linked into centrosymmetric dimers by a pair of N—H⋯O hydrogen bonds. The ethyl group is disordered over two positions in a ratio of 0.758 (6):0.242 (6).

Partial Text

For pharmaceutical usage of derivatives of isoquinoline-1,3(2H,4H)-dione, see: Lu et al. (2010 ▶); Tsou et al. (2008 ▶, 2009 ▶); Billamboz et al. (2011 ▶).