Research Article: Ethyl 7-methyl-3-oxo-5-phenyl-2-(2,4,6-trimeth­oxy­benzyl­idene)-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Noor Afshan Banu, V. Bheema Raju.


In the title compound, C26H26N2O6S, the benzene ring is positioned axially to the thia­zolopyrimidine ring and bis­ects it with a dihedral angle of 80.94 (7)°. The pyrimidine ring adopts a flattened boat conformation. In the crystal, pairs of bifurcated C—H⋯O hydrogen bonds link the mol­ecules into chains along the c axis.

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For the pharmacological activity of pyrimidine derivatives, see: Alam et al. (2010 ▶). For a related crystal structure, see: Chen et al. (2012 ▶).