Research Article: Glucose‐Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid

Date Published: February 13, 2017

Publisher: John Wiley and Sons Inc.

Author(s): Ali K. Yetisen, Nan Jiang, Afsoon Fallahi, Yunuen Montelongo, Guillermo U. Ruiz‐Esparza, Ali Tamayol, Yu Shrike Zhang, Iram Mahmood, Su‐A Yang, Ki Su Kim, Haider Butt, Ali Khademhosseini, Seok‐Hyun Yun.


Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide‐co‐poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis‐diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.

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