Research Article: Methyl 1-ethyl-7-methyl-4-oxo-1,4-di­hydro-1,8-naphthyridine-3-carboxyl­ate monohydrate

Date Published: March 01, 2012

Publisher: International Union of Crystallography

Author(s): Rehana Yasmeen, Muhammad Zia-ur-Rehman, Muhammad Azim Khattak, Muhammad Nadeem Arshad, Islam Ullah Khan.

http://doi.org/10.1107/S1600536812004333

Abstract

In the structure of the title compound, C13H14N2O3·H2O, all atoms of the organic molecule except the terminal methyl group of the ethyl group attached to the N atom of the pyridinone ring are roughly coplanar, with an r.m.s. deviation of 0.0897 Å. In the crystal, C—H⋯O contacts link pairs of naphthyridine mol­ecules into head-to-tail dimers. These are joined by strong O—H⋯O hydrogen bonds from the water molecules into infinite chains along the a axis.

Partial Text

For the coordination properties of 1,8-naphthyridine ligands, see: Gavrilova & Bosnich (2004 ▶); Mintert & Sheldrick (1995 ▶). For their biological activity, see: Chen et al. (2001 ▶); Ferrarini et al. (2000 ▶); Roma et al. (2000 ▶). For related structures, see: Deeba, Khan, Zia-ur-Rehman, Çaylak & Şahin (2009 ▶); Deeba, Khan, Zia-ur-Rehman, Şahin & Çaylak (2009 ▶). For graph-set notation, see: Bernstein et al. (1995 ▶).

 

Source:

http://doi.org/10.1107/S1600536812004333