Research Article: Methyl 2-{1-[(Z)-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl­idene]ethyl­amino}-3-phenyl­propanoate

Date Published: June 01, 2010

Publisher: International Union of Crystallography

Author(s): Hualing Zhu, Jun Shi, Zhen Wei, Ronghua Dai, Xin Zhang.


The mol­ecule of the title compound, C22H23N3O3, exists in the enamine–keto form. A strong intra­molecular N—H⋯O hydrogen bond occurs, generating an S(6) ring. The dihedral angle between the heterocycle and the adjacent phenyl ring is 3.75 (15)°.

Partial Text

For the anti­bacterial activity of Schiff bases derived from 4-acyl-5-pyrazolones and metal complexes, see: Li et al. (1997 ▶, 2004 ▶). For the biological activity of amino acid esters, see: Xiong et al. (1993 ▶). For related structures, see: Wang et al. (2003 ▶); Zhang et al. (2004 ▶, 2010 ▶); Zhu et al. (2005 ▶).




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