Research Article: Methyl 2-({6-[(1-meth­oxy-2-methyl-1-oxopropan-2-yl)carbamo­yl]pyridin-2-yl}formamido)-2-methyl­propano­ate

Date Published: May 01, 2012

Publisher: International Union of Crystallography

Author(s): Mohamed A. Al-Omar, Abdel-Galil E. Amr, Hazem A. Ghabbour, Ching Kheng Quah, Hoong-Kun Fun.


In the title compound, C17H23N3O6, the two meth­oxy­carbonyl C—O—C=O planes are inclined at dihedral angles of 5.3 (4) and 83.9 (4)° with respect to the central pyridine ring. An intra­molecular N—H⋯O hydrogen bond generates an S(5) ring motif. In the crystal, mol­ecules are linked into a chain along the c axis via C—H⋯O hydrogen bonds.

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For general background to and the pharmacological activity of the title compound, see: Abou-Ghalia & Amr (2004 ▶); Abou-Ghalia et al. (2003 ▶); Al-Omar & Amr (2010 ▶); Amr (2000 ▶); Attia et al. (1997 ▶, 2000 ▶); Amr et al. (2009 ▶); Fakhr et al. (2008 ▶). For standard bond-length data, see: Allen et al. (1987 ▶). For hydrogen-bond motifs, see: Bernstein et al. (1995 ▶).