Research Article: Methyl 2,6-diphenyl-1-p-tolyl-4-(p-tolyl­amino)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate

Date Published: August 01, 2012

Publisher: International Union of Crystallography

Author(s): K. N. Venugopala, Susanta K. Nayak, Bharti Odhav.


In the title compound, C33H32N2O2, the tetra­hydro­pyridine ring adopts a boat conformation with the carbonyl group in an s-cis conformation with respect to the C=C bond of the six-membered tetra­hydro­pyridine ring. The mol­ecular conformation is stabilized by intra­molecular N—H⋯O, C—H⋯O and C—H⋯π inter­actions. Formation of centrosymmetric head-to-head dimers is observed through pairwise inter­molecular N—H⋯O hydrogen bonds. Additional weak C—H⋯O and C—H⋯π inter­actions stabilize the three-dimensional mol­ecular assembly.

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For background to the applications of piperidines, see: Pearson et al. (2005 ▶); Sakai et al. (1986 ▶); Nayak et al. (2011 ▶); Mishra & Ghosh (2011 ▶). For ring-puckering parameters, see: Cremer & Pople (1975 ▶).




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