Research Article: Methyl 3-[ferrocen­yl(hydr­oxy)meth­yl]-1-methyl-2′-oxospiro­[pyrrolidine-2,3′-indoline]-3-carboxyl­ate

Date Published: May 01, 2009

Publisher: International Union of Crystallography

Author(s): E. Theboral Sugi Kamala, S. Nirmala, L. Sudha, S. Kathiravan, R. Raghunathan.


In the title compound, [Fe(C5H5)(C20H21N2O4)], the pyrrolidine ring exhibits an envelope conformation with the spiro-C atom deviating from the plane of the remaining four atoms. The pyrrolidine ring is almost perpendicular to the indolinone ring [dihedral angle = 87.52 (7)°]. The structure is stabilized by an intra­molecular O—H⋯N hydrogen bond and by inter­molecular C—H⋯O and N—H⋯O inter­actions.

Partial Text

For general background to the spiro-indole-pyrrolidine ring system, see: Cordell (1981 ▶). For the biological activity of pyrrolidine-containing compounds and their use in catalysis, see: Witherup et al. (1995 ▶); Kravchenko et al. (2005 ▶). For the biological activity of oxindole derivatives, see: Glover et al. (1998 ▶); Bhattacharya et al. (1982 ▶). For puckering and asymmetry parameters, see: Cremer & Pople (1975 ▶); Nardelli (1983 ▶).




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