Research Article: N′2,N′5-Bis[(E)-2-hy­droxy­benzyl­idene]-3,4-dimethyl­thio­phene-2,5-dicarbohydrazide

Date Published: June 01, 2012

Publisher: International Union of Crystallography

Author(s): Shao-Lin Zhang, Ling Zhang, Qin-Mei Wen, Rong-Xia Geng, Cheng-He Zhou.


In the title mol­ecule, C22H20N4O4S, both C=N bonds are in an E conformation. The benzene rings form dihedral angles of 12.10 (13) and 25.17 (12)° with the thio­phene ring. The dihedral angle between the two benzene rings is 17.59 (14)°. There are two intra­molecular O—H⋯N hydrogen bonds. In the crystal, N—H⋯O hydrogen bonds connect mol­ecules into chains along [010].

Partial Text

For the medicinal properties of thio­phene derivatives, see: Bondock et al. (2010 ▶); Geng & Zhou (2008 ▶). For a related structure, see: Tang et al. (2010 ▶).




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