Research Article: N-(1-Acetyl-5-benzoyl-1,4,5,6-tetra­hydro­pyrrolo­[3,4-c]pyrazol-3-yl)benzamide

Date Published: June 01, 2012

Publisher: International Union of Crystallography

Author(s): Xiao-Guang Bai, Ju-Xian Wang, Yu-Cheng Wang.


In the mol­ecule of the title compound, C21H18N4O3, the fused pyrrolo­[3,4-c]pyrazole ring system is approximately planar [maximum deviation = 0.0486 (16) Å] and forms dihedral angles of 87.21 (8) and 35.46 (7)° with the phenyl rings. In the crystal, N—H⋯O and C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions link the mol­ecules into chains parallel to [201].

Partial Text

For background to potential anti­cancer kinase inhibitors, see: Fancelli et al. (2005 ▶); Gadekar et al. (1968 ▶). For the structures of related compounds synthesized by our group, see: Guo et al. (2010 ▶); Xia et al. (2011 ▶).




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