Date Published: February 01, 2012
Publisher: International Union of Crystallography
Author(s): Saeed Balalaie, Yaghoub Haghighatnia, Frank Rominger, Vahid Amani.
In the title compound, C19H23IN2O2, the cyclohexane ring adopts a chair conformation, and the mean plane of the propiolamide unit is approximately perpendicular to the benzene ring [dihedral angle = 88.12 (13)°]. Weak intramolecular C—H⋯O hydrogen bonding is observed between the carbonyl group and the benzene ring. In the crystal, classical N—H⋯O hydrogen bonds and weak C—H⋯O interactions are present.
For background to multi-component reactions (MCRs), see: Dömling & Ugi (2000 ▶); Tietze (1996 ▶); Tietze et al. (2006 ▶); Dömling (2006 ▶); Zhu & Bienayme (2005 ▶).