Research Article: N-[2-(N-Cyclo­hexyl­carbamo­yl)propan-2-yl]-N-(2-iodo­phen­yl)prop-2-ynamide

Date Published: February 01, 2012

Publisher: International Union of Crystallography

Author(s): Saeed Balalaie, Yaghoub Haghighatnia, Frank Rominger, Vahid Amani.

http://doi.org/10.1107/S1600536811055140

Abstract

In the title compound, C19H23IN2O2, the cyclo­hexane ring adopts a chair conformation, and the mean plane of the propiolamide unit is approximately perpendicular to the benzene ring [dihedral angle = 88.12 (13)°]. Weak intra­molecular C—H⋯O hydrogen bonding is observed between the carbonyl group and the benzene ring. In the crystal, classical N—H⋯O hydrogen bonds and weak C—H⋯O inter­actions are present.

Partial Text

For background to multi-component reactions (MCRs), see: Dömling & Ugi (2000 ▶); Tietze (1996 ▶); Tietze et al. (2006 ▶); Dömling (2006 ▶); Zhu & Bienayme (2005 ▶).

 

Source:

http://doi.org/10.1107/S1600536811055140