Research Article: N-[3-(2-Methyl­phen­yl)isoquinolin-1-yl]formamide

Date Published: May 01, 2009

Publisher: International Union of Crystallography

Author(s): Fu Na Cui, Jun Qi Li, Xiao Li Chen, Qing Bao Song.

http://doi.org/10.1107/S1600536809011714

Abstract

The title compound, C17H14N2O, crystallizes as a cis formamide isomer. The isoquinoline and benzene fragments are nearly perpendicular [dihedral angle = 81.79 (18)°], whereas the formamide group is virtually coplanar with the isoquinoline unit [dihedral angle = 1.66 (15)°]. Inter­molecular N—H⋯O hydrogen bonds link mol­ecules into a centrosymmetric dimer.

Partial Text

For the cytotoxic activity of aryl­isoquinolines, see: Cho et al. (2002 ▶, 2003 ▶). For the synthethic procedures relevant to this work, see: Nunno et al. (2008 ▶); Tovar & Swager (1999 ▶); Cho et al. (2002 ▶).

 

Source:

http://doi.org/10.1107/S1600536809011714

 

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