Date Published: May 01, 2009
Publisher: International Union of Crystallography
Author(s): Fu Na Cui, Jun Qi Li, Xiao Li Chen, Qing Bao Song.
The title compound, C17H14N2O, crystallizes as a cis formamide isomer. The isoquinoline and benzene fragments are nearly perpendicular [dihedral angle = 81.79 (18)°], whereas the formamide group is virtually coplanar with the isoquinoline unit [dihedral angle = 1.66 (15)°]. Intermolecular N—H⋯O hydrogen bonds link molecules into a centrosymmetric dimer.
For the cytotoxic activity of arylisoquinolines, see: Cho et al. (2002 ▶, 2003 ▶). For the synthethic procedures relevant to this work, see: Nunno et al. (2008 ▶); Tovar & Swager (1999 ▶); Cho et al. (2002 ▶).