Date Published: June 01, 2012
Publisher: International Union of Crystallography
Author(s): Farhana Aman, Waseeq Ahmad Siddiqui, Adnan Ashraf, Hamid Latif Siddiqui, Masood Parvez.
In the title molecule, C17H16N2O4S, the heterocyclic thiazine ring adopts a half-chair conformation, with the S and N atoms displaced by 0.546 (4) and 0.281 (4) Å, respectively, on opposite sides of the mean plane formed by the remaining ring atoms. The molecular structure is stabilized by an intramolecular O—H⋯O hydrogen bond. The two aromatic rings are inclined to one another by 42.32 (11)°. In the crystal, molecules are linked by pairs of N—H⋯O hydrogen bonds, forming inversion dimers. The dimers are linked via a series of C—H⋯O interactions, leading to the formation of a three-dimensional network.
For the biological activity of benzothiazine derivatives, see: Lomabardino & Wiseman et al. (1972 ▶); Lazzeri et al. (2001 ▶). For the synthetic procedure, see: Siddiqui et al. (2008 ▶). For the structures of similar compounds, see: Siddiqui et al. (2008 ▶, 2009 ▶).